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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLEK
All Species:
24.55
Human Site:
T298
Identified Species:
54
UniProt:
P08567
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P08567
NP_002655.2
350
40097
T298
H
L
R
G
C
V
V
T
S
V
E
S
N
S
N
Chimpanzee
Pan troglodytes
XP_515524
350
40124
T298
H
L
R
G
C
V
V
T
S
V
E
S
N
S
N
Rhesus Macaque
Macaca mulatta
XP_001094492
350
40060
T298
H
L
R
G
C
V
V
T
S
V
E
S
N
S
N
Dog
Lupus familis
XP_537486
375
42096
S324
S
L
R
G
S
L
V
S
A
L
E
D
N
G
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9JHK5
350
39882
T298
H
L
R
G
C
V
V
T
S
V
E
S
S
H
D
Rat
Rattus norvegicus
Q4KM33
350
39977
T298
H
L
R
G
C
V
V
T
S
V
E
S
N
P
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512767
334
37917
T282
H
L
R
G
C
V
V
T
A
V
E
D
S
P
D
Chicken
Gallus gallus
NP_990194
353
40280
A301
L
R
G
C
V
V
T
A
V
E
D
M
P
D
S
Frog
Xenopus laevis
NP_001080021
289
33430
F238
S
S
D
D
D
A
L
F
K
E
E
F
R
G
N
Zebra Danio
Brachydanio rerio
NP_957135
352
40176
A300
L
R
G
S
V
V
T
A
V
E
F
V
P
D
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781827
375
42698
A322
C
T
V
G
V
Q
E
A
R
E
K
S
D
V
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
99.1
36
N.A.
92
92
N.A.
80.5
81.5
63.1
67.3
N.A.
N.A.
N.A.
N.A.
34.4
Protein Similarity:
100
100
100
55.7
N.A.
96.8
97.1
N.A.
89.4
90.6
73.7
83.8
N.A.
N.A.
N.A.
N.A.
53.3
P-Site Identity:
100
100
100
40
N.A.
80
86.6
N.A.
66.6
6.6
13.3
6.6
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
100
66.6
N.A.
93.3
93.3
N.A.
86.6
20
20
6.6
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
10
0
28
19
0
0
0
0
0
10
% A
% Cys:
10
0
0
10
55
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
10
10
0
0
0
0
0
10
19
10
19
28
% D
% Glu:
0
0
0
0
0
0
10
0
0
37
73
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
10
0
0
10
10
0
0
0
% F
% Gly:
0
0
19
73
0
0
0
0
0
0
0
0
0
19
0
% G
% His:
55
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
10
0
10
0
0
0
0
% K
% Leu:
19
64
0
0
0
10
10
0
0
10
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
46
0
37
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
19
19
0
% P
% Gln:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
19
64
0
0
0
0
0
10
0
0
0
10
0
0
% R
% Ser:
19
10
0
10
10
0
0
10
46
0
0
55
19
28
10
% S
% Thr:
0
10
0
0
0
0
19
55
0
0
0
0
0
0
10
% T
% Val:
0
0
10
0
28
73
64
0
19
55
0
10
0
10
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _